POLYNUCLEOTIDES
MAIDSTONE KENT

Think of polynucleotides as messengers for your skin cells.

They're injectable biostimulators made from highly purified DNA fragments. But here's what matters: they don't add volume like fillers or freeze muscles like botulinum toxin. Instead, they activate your skin's own repair mechanisms at a cellular level.

In my cardiac days, I watched patients heal from the inside out.

That's exactly what polynucleotides do for your skin. They stimulate fibroblasts, boost collagen production, and improve microcirculation. The result? Healthier, more resilient skin that looks refreshed because it genuinely is.

Let me break down the science.

Polynucleotides are long chains of nucleotides, the building blocks of DNA. When I inject them into your skin, they trigger multiple biological processes simultaneously:

Fibroblast activation: These cells produce collagen and elastin, the structural proteins that keep skin firm and elastic.

Tissue regeneration: Polynucleotides enhance cellular repair and improve blood flow to your dermal tissue, supporting healthier skin structure from within.

Deep hydration: They attract and bind water molecules at a cellular level, restoring that plump, dewy texture everyone wants.

Antioxidant protection: They neutralize free radicals, shielding your skin cells from oxidative stress caused by UV exposure, pollution, and natural aging.

Polynucleotides excel at tissue repair and regeneration, which makes them incredibly versatile.

At Juvenology Clinic, I use them to address:

• Fine lines and wrinkles

• Crepey, thinning skin on the face, neck, or décolletage

• Dull, uneven skin tone

• Loss of elasticity

• Scarring, including acne scars

• Under-eye hollows, dark circles, and tired-looking skin

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They work beautifully for prevention in your 30s and restoration in your 50s, 60s, and beyond. Your skin doesn't stop responding to biological signals just because you age. It just needs the right support.

I treat multiple areas depending on your anatomy and goals:

• Face: Cheeks, temples, perioral region, jawline

• Eyes: Under-eye hollows, fine lines, dark circles

• Neck and décolletage: Areas prone to crepiness and sun damage

• Hands: For texture and skin quality improvement

• Scalp: To support skin and hair follicle health

In clinic, I assess your facial structure, skin quality, and vascular anatomy before planning your treatment. Polynucleotides also combine beautifully with Profhilo, microneedling, or PRP for enhanced regenerative results.

The procedure takes 20 to 30 minutes.

I use a series of small, precise injections with a fine needle or cannula, targeting specific areas based on your skin's needs. Most patients tolerate this well. If you're sensitive, I can apply a topical numbing cream beforehand.

Here's what sets my approach apart: I never skip anatomical mapping.

My cardiac nursing background taught me that knowing exactly where vessels run, understanding tissue layers, and respecting anatomy can prevent complications. Every injection I make is deliberate. I'm not just treating skin. I'm treating the dermal and subdermal structures beneath it.

Precision matters.

A standard course involves three sessions, spaced two to three weeks apart.

This allows your skin time to respond and remodel gradually. Think of it as training your fibroblasts to work more efficiently. One session provides a signal. Three sessions create a sustained regenerative response.

Maintenance treatments every six to nine months help preserve and extend your results over time.

You'll notice improved hydration within days. Your skin will feel softer, plumper, more comfortable.

But the real transformation happens over four to eight weeks as your fibroblasts respond and collagen remodeling begins. Texture improves. Fine lines soften. Your skin tone becomes more even and radiant.

This is biological regeneration, not instant volume correction. The results build gradually because your skin is genuinely healing.

Most patients enjoy visible improvement for six to twelve months, depending on age, lifestyle, and baseline skin condition.

Regular maintenance sessions extend these effects. Many of my patients schedule treatments every six to nine months to keep their skin in optimal regenerative condition.

Minimal.

You might experience mild redness, swelling, or small bumps at injection sites for 24 to 48 hours. Bruising is uncommon but possible.

Most people return to normal activities immediately. I advise avoiding makeup, strenuous exercise, saunas, and alcohol for 24 hours post-treatment to minimize inflammation and optimize healing.

Yes.

Polynucleotides are derived from purified salmon DNA, chosen specifically for its close compatibility with human tissue. The purification process removes any proteins that could trigger immune reactions, making the treatment highly biocompatible.

Clinical studies support their safety and efficacy in tissue regeneration.

At Juvenology Clinic, all procedures follow strict medical protocols. Your treatment will only ever be performed by a registered healthcare professional in a sterile, clinical environment.

Great question. They're both injectable biostimulators that improve skin quality, but they work differently. Many of my patients alternate or combine both treatments for comprehensive skin rejuvenation. Polynucleotides repair and regenerate. Profhilo hydrates and firms. Together, they're incredibly powerful.

You're an ideal candidate if you:

• Have tired, dehydrated, or aging skin

• Want natural, subtle rejuvenation without dramatic volume changes

• Prefer treatments that work with your body's biology

• Are looking for tissue repair rather than structural alteration

I often recommend polynucleotides to patients who want to improve skin quality, not change their appearance. This isn't about looking different. It's about looking like yourself, just healthier and more rested.

Side effects are rare and temporary: mild swelling, bruising, or tenderness at injection sites.

Because polynucleotides are naturally derived and biocompatible, allergic reactions are extremely uncommon. The main risks in any injectable treatment come from poor technique or lack of anatomical knowledge.

At Juvenology, every treatment follows the same evidence-based protocols I learned in hospital practice. I map your vascular anatomy. I use sterile technique. I respect tissue planes.

You're not getting a beauty treatment. You're getting a medical procedure performed by a medically trained injector.

Absolutely. Combining treatments is often the key to optimal results.

Polynucleotides work beautifully alongside:

• Microneedling or PRP to enhance collagen induction and regeneration

• Profhilo for deeper hydration and skin laxity

• Dermal fillers for structural support

• Botulinum toxin to soften expression lines

Your treatment plan will always be personalized after a thorough consultation and anatomical assessment.

Every polynucleotide treatment at Juvenology is:

• Performed by an NMC-registered nurse with advanced anatomical expertise

• Based on clinical evidence, not trends

• Tailored to your unique skin biology and facial structure

• Delivered in a sterile, CQC-compliant medical environment

My philosophy is simple: regenerative treatments should be safe, scientific, and subtle. You should look like yourself, just fresher, healthier, and more confident.