What are Polynucleotides?
Polynucleotides (PDRN - polydeoxyribonucleotide) are DNA fragments derived from salmon or trout DNA, purified and biocompatible with human tissue.
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DNA-based regeneration
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Anti-inflammatory action
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Promotes angiogenesis
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Stimulates fibroblasts
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Accelerates wound healing
At my Maidstone clinic, I use polynucleotides for patients whose skin has genuine damage: sun damage, scarring, thin crepey tissue, or inflammation. This isn't about looking younger. It's about repairing damaged tissue at a cellular level.
How do polynucleotides work?
Step 1: Receptor activation
Polynucleotides bind to A2A adenosine receptors on cell surfaces, triggering multiple repair pathways simultaneously.
Step 2: Anti-inflammatory response
Inflammatory markers decrease. Reactive oxygen species reduce. Your skin's chronic low-grade inflammation calms.
Step 3: Angiogenesis
New blood vessel formation improves tissue perfusion. Better blood flow means better nutrient delivery and waste removal.
Step 4: Fibroblast stimulation
Your fibroblasts (collagen-producing cells) activate. Collagen synthesis increases. Tissue structure improves.
Step 5: Cellular repair
Damaged cells receive repair signals. DNA repair mechanisms activate. Cellular function improves.
The result? Healthier, more resilient tissue. Improved texture. Reduced scarring. Better overall skin quality.
What can polynucleotides treat in Maidstone?
Polynucleotide treatment excels at repairing damaged tissue and improving skin that's genuinely compromised.
Sun-damaged and Photo-damaged Skin
Years of UV exposure damage cellular DNA and degrade collagen. Your skin becomes thin, crepey, uneven in tone and texture. Polynucleotides stimulate DNA repair mechanisms and collagen regeneration. Over 3-4 months, photodamaged skin improves remarkably: thicker, more resilient, better texture. Severe sun damage, chest and décolletage aging, hand rejuvenation.
Acne Scarring
Scarring involves disrupted collagen architecture and impaired healing. Polynucleotides promote proper tissue remodeling and collagen reorganization.
Under-Eye Rejuvenation
The under-eye area has extremely thin skin prone to crepiness, darkness, and hollow appearance. Polynucleotides thicken skin, improve circulation, and enhance tissue quality.
Inflammatory Skin
Chronic inflammation damages skin at a cellular level. Polynucleotides' anti-inflammatory properties calm reactive skin while promoting repair. Rosacea-prone skin, post-inflammatory damage, sensitized skin.
Crepey Skin
Areas with thin ageing skin respond beautifully. The tissue-repairing effects thicken skin, improve texture, restore resilience. Neck aging, chest wrinkles, hand rejuvenation, thin crepey skin.
Hair Restoration
Polynucleotides injected into the scalp improve blood flow to follicles, reduce inflammation, and stimulate hair growth. Increasingly popular for pattern hair loss and thinning. Androgenic alopecia, overall hair density, scalp health
Polynucleotides vs Other Treatments
Polynucleotides vs Profhilo
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Polynucleotides: DNA-based repair, anti-inflammatory, treats damaged tissue, tissue regeneration
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Profhilo: HA-based hydration, bio-remodelling, improves elasticity, tissue quality
Both improve skin, different mechanisms. Often combined for comprehensive results.
Polynucleotides vs skin boosters
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Polynucleotides: Stimulate cellular repair mechanisms, DNA-level regeneration
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Skin boosters: Hydration-focused, surface improvement
Polynucleotides work deeper at cellular function level.
Polynucleotides vs exosomes
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Polynucleotides: DNA fragments, adenosine receptor activation, proven track record
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Exosomes: Growth factor delivery, cellular communication, emerging evidence
Both are regenerative. Polynucleotides have longer clinical history in medicine.
Polynucleotides vs microneedling
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Polynucleotides: Injectable regenerative treatment, cellular-level repair
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Microneedling: Wound healing response, collagen induction
Can be combined: microneedling creates channels, polynucleotides deliver regenerative signals.
Polynucleotides vs PRP
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Polynucleotides: Pharmaceutical-grade DNA fractions, consistent dosing
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PRP: Your own growth factors, variable concentration
Polynucleotides often show more consistent, dramatic results.
Polynucleotides Treatment Prices in Maidstone
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Single treatment: £250
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Lumi Eyes Special Offer: £300 for 3
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3 for 2 Special Offer: £450
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Scalp treatment: £250 per treatment
Package pricing highly recommended as single treatments rarely deliver optimal results.
You're paying for:
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Pharmaceutical-grade polynucleotides (authentic product, properly stored)
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Medical expertise in injection technique and treatment planning
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Comprehensive assessment of whether polynucleotides suit your concerns
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Follow-up monitoring of tissue response and results
At Juvenology Clinic, I only use verified polynucleotide products from authorized medical suppliers. The market has alternatives and counterfeits. Authenticity matters for safety and results.