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Spread your payments over 3–12 months
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Frequently Asked Questions
- 01
Profhilo is injectable hyaluronic acid, but here's what makes it different from everything else I use in clinic. It's not a filler. It's not adding volume or changing your facial structure. It's bio-remodelling.
Let me explain what that means. Profhilo contains one of the highest concentrations of hyaluronic acid available, 64 milligrams per 2 milliliter syringe. But unlike dermal fillers where the HA is cross-linked into a gel that stays in one place, Profhilo uses a patented thermal bonding process. The HA molecules are stabilized without chemical cross-linkers.
What does this mean for your skin? The product spreads. It diffuses through tissue planes instead of sitting as a discrete deposit. As it spreads, it triggers fibroblast activity. Those are the cells responsible for making collagen and elastin. So you're not just getting hydration. You're stimulating your skin to rebuild its structural proteins from within.
I often describe Profhilo to patients as injectable skin quality. It's one of the most elegant treatments in aesthetic medicine because it works with your biology, not against it.
- 02
Here's the science, and I find this genuinely fascinating.
When I inject Profhilo into specific anatomical points, it begins dispersing through the dermis. The high concentration of hyaluronic acid creates what's called a hydrating depot. That HA attracts water molecules, obviously, but the real magic is the biochemical signaling.
The presence of concentrated HA triggers fibroblasts to upregulate collagen type I and elastin production. We're talking about measurable increases in these structural proteins. Studies show significant improvement in dermal thickness and elasticity after Profhilo treatment.
Anatomically speaking, we're working in the dermal layer where aging manifests as collagen degradation, elastin fragmentation, and dehydration. Profhilo addresses all three simultaneously. It hydrates, it stimulates new collagen synthesis, and it improves elastin fiber quality.
What I love about this from a nursing perspective is that it's evidence-based. The studies exist. The histological data exists. This isn't marketing hype. This is measurable biological remodeling.
- 03
I most commonly treat faces and necks. These areas show aging dramatically because the skin is thin and constantly exposed to environmental damage. Profhilo restores that plumpness and glow that disappears with age.
But here's what many people don't realize. Profhilo works beautifully on the décolletage, especially if you've got that crepey chest texture from sun damage or sleeping on your side. Hands are another excellent area. Hand skin is notoriously thin and shows aging early. Profhilo can genuinely restore volume and smoothness.
I've also treated upper arms for crepey skin, even knees and abdomen in specific cases where skin laxity is the primary concern. The key is having enough viable fibroblasts in the tissue. Dead, severely sun-damaged skin won't respond as well.
During consultation, I'll assess your skin quality, laxity, and hydration status. I'll tell you honestly where Profhilo will help and where other treatments might be more appropriate.
- 04
I use a very specific injection technique called the BAP technique. That stands for Bio Aesthetic Points. There are five predetermined points on each side of the face, mapped based on facial anatomy and lymphatic drainage pathways.
Why these specific points? Because Profhilo's spread pattern has been studied extensively. Injecting at these precise locations ensures optimal product distribution across the entire face without overfilling any single area. It's beautifully strategic.
I mark your face first so you can see exactly where I'm injecting. Then I use a very fine needle to place small amounts of Profhilo at each point. You'll feel a sharp pinch and maybe some stinging as the product goes in, but it's quick. Most patients tolerate it well without anesthetic.
The entire treatment takes maybe 15 to 20 minutes. No numbing cream needed for most people, though I can apply it if you're particularly sensitive.
After injection, you'll see small bumps at each point. These are temporary and flatten within 12 to 24 hours as the product disperses. That's completely normal. That's the Profhilo doing exactly what it should do, spreading through your tissue.
- 05
The standard protocol is two sessions spaced exactly four weeks apart. This isn't arbitrary. The timing is based on how long it takes for the biological remodeling process to occur.
First treatment triggers the initial collagen and elastin stimulation. Four weeks later, your fibroblasts are actively producing new proteins. The second treatment amplifies that response and sustains it for months.
Some patients, particularly those with more advanced skin aging or severe laxity, benefit from a third session. I'll assess this during your follow-up.
For maintenance, most people return every 6 to 9 months. Some stretch it to a year. It depends on your age, skin quality, lifestyle factors like sun exposure and smoking, and how quickly your body breaks down hyaluronic acid.
- 06
Profhilo is not instant gratification. Let me be clear about the timeline.
Within the first week or two, you'll notice improved hydration. Your skin feels softer. Maybe you need less moisturizer. There's a subtle glow. But you're not dramatically different yet.
The real transformation happens between 4 and 8 weeks after your second treatment. That's when collagen synthesis peaks.
That's when you'll notice genuine firmness, reduced fine lines, improved texture. People tell me their skin looks healthier, more radiant, like they're sleeping better and drinking more water even when they're not.
This gradual timeline frustrates some patients who want immediate results. I understand. But biological processes take time. You cannot rush fibroblast activity. You cannot force collagen synthesis to happen overnight. Profhilo works with your body's natural healing mechanisms, and those mechanisms have their own pace.
Anyone promising you dramatic transformation in days is overselling. I prefer honest timelines over unrealistic promises.
- 07
Minimal. Most patients walk out and get on with their day.
Immediately after treatment, you'll have visible bumps at the injection sites. They look like mosquito bites. Don't panic. This is completely normal and expected. The bumps flatten within 12 to 24 hours as the Profhilo disperses through your tissue.
You might have slight redness or tenderness. Occasionally, minor bruising if I've nicked a tiny superficial vessel. These effects resolve quickly, usually within 48 hours.
Here's my aftercare protocol. Avoid touching or massaging the treated area for at least 6 hours so the product can begin spreading naturally. Skip intense exercise for 24 hours because increased blood flow and sweating can affect distribution. No makeup for 24 hours to minimize infection risk. Avoid saunas, steam rooms, or very hot showers for 48 hours.
Most of my patients schedule Profhilo during a lunch break or after work. You're slightly bumpy for a day, but you're functional.
- 08
Profhilo has an excellent safety profile when administered correctly.
It's CE certified, backed by extensive clinical studies, and used globally. The thermal bonding process means no chemical cross-linkers like BDDE are used. That significantly reduces the risk of inflammatory reactions compared to some traditional fillers.
Allergic reactions to hyaluronic acid itself are extremely rare because HA is a naturally occurring substance in human tissue. Your body recognizes it. If reactions occur, they're usually related to impurities in the product or contamination during administration, not the HA itself.
That said, any injectable treatment carries theoretical risks. Infection if sterile technique isn't followed. Bruising or swelling from needle trauma. Very rarely, vascular complications if product is accidentally injected into a blood vessel, though this risk is much lower with Profhilo than with viscous fillers.
In my cardiac days at KIMS Hospital, I learned that safety is about protocol adherence. Sterile technique. Proper product handling. Anatomical knowledge. Emergency preparedness. I bring that same rigor to every Profhilo treatment.
I perform a thorough medical assessment before treating anyone. I follow aseptic protocols meticulously. I know my facial vascular anatomy. I inject slowly and carefully. Safety is non-negotiable.
- 09
Profhilo works best for people noticing early to moderate skin aging. That typically means patients in their 30s, 40s, 50s, even 60s if skin quality is still reasonable.
You're a good candidate if you have skin that's losing hydration, developing fine lines or crepey texture, feeling less firm or elastic. If you're noticing that your skin just doesn't look as healthy and glowing as it used to. If your makeup sits differently because your skin texture has changed.
Profhilo is also brilliant for preventative treatment. If you're in your 30s and want to maintain skin quality before significant aging occurs, this is an excellent option.
You're not a good candidate if you have severe skin laxity where surgical intervention would be more appropriate. Profhilo improves quality. It doesn't perform miracles on skin that's severely damaged or aged. I'll be honest during consultation if I think other treatments would serve you better.
Active skin infections, pregnancy, breastfeeding, known allergies to HA products, these are all contraindications I assess during medical screening.
- 10
This is crucial to understand because patients often confuse them.
Dermal fillers add volume. They're designed to restore structural support, lift cheeks, plump lips, fill deep folds. The gel sits where I place it. It creates shape.
Profhilo doesn't add volume or change shape. It spreads through tissue to improve skin quality itself. It's treating the dermal layer, not the subcutaneous fat or deep facial structure. It's about hydration, firmness, texture, and glow.
I use both in my practice, often in combination. Filler restores structural volume loss. Profhilo improves the quality of the skin overlying that structure. Together, they create comprehensive facial rejuvenation.
Think of it like renovating a house. Filler is structural repair, fixing the foundation and framework. Profhilo is refinishing the surfaces, making everything look polished and well-maintained. You often need both.
- 11
Most patients maintain visible results for 6 to 9 months after completing the initial two-session course.
But here's what affects longevity. Your age and baseline skin quality matter. Younger skin with better fibroblast activity holds results longer. Your metabolism affects how quickly you break down hyaluronic acid. Lifestyle factors like smoking, sun exposure, and hydration status impact collagen and elastin maintenance.
With regular maintenance treatments every 6 to 9 months, many patients notice cumulative improvement. Their skin quality continues to enhance over time because we're sustaining that collagen and elastin production consistently.
Profhilo isn't permanent. Nothing in aesthetics is except surgery, and even surgical results change with ongoing aging. But it's one of the longer-lasting non-surgical skin treatments available.
- 12
Absolutely, and I often recommend it for comprehensive results.
Profhilo pairs beautifully with Botox. Botox relaxes the muscles creating dynamic wrinkles. Profhilo improves the quality of the skin where those wrinkles form. Together, you get smoother movement and better skin texture.
It also works well with dermal fillers. Filler restores volume, Profhilo improves skin quality. The combination creates more natural, cohesive results than either treatment alone.
I sometimes layer Profhilo with medical-grade peels or
microneedling for patients who need surface texture improvement alongside deeper remodeling. The key is proper timing. I space treatments appropriately to avoid overwhelming the skin or causing unnecessary inflammation.
During consultation, I'll assess your concerns comprehensively and recommend a treatment plan that addresses multiple aspects of aging safely and effectively.
- 13
Let's talk about what's normal versus what's concerning.
Normal, expected effects include those temporary bumps at injection sites that resolve within 24 hours. Mild redness or tenderness. Occasional bruising, especially if you're on blood thinners or supplements like fish oil that affect clotting.
These aren't complications. They're normal tissue responses to injection.
Rare complications include infection if sterile technique is compromised. Allergic reactions to the product itself, though these are exceptionally uncommon with ultrapure HA. Vascular compromise if product accidentally enters a blood vessel, though again, this risk is very low with Profhilo's fluid consistency.
Granulomas or nodules are possible with any HA product but rare with Profhilo due to its high purity and lack of chemical cross-linkers.
How do I minimize risks? Thorough medical screening. Meticulous sterile technique. Precise anatomical knowledge. Slow, careful injection. Immediate recognition of any adverse signs.
In over a decade of practice, serious complications are extraordinarily rare. But they're the reason I take safety protocols seriously.
- 14
I'll give you transparent pricing during consultation with no obligation to proceed. I don't believe in pressure tactics or hidden fees.
Here's what you're paying for. Medical-grade product from an authorized supplier. Registered nurse administration with advanced anatomical training. Comprehensive medical assessment. Strict sterile protocols. Follow-up care and review.
Cheaper Profhilo often means compromised safety. Maybe the practitioner isn't medically qualified. Maybe sterile technique is inadequate. Maybe the product isn't genuine. Those savings aren't worth the risk to your face.
- 15
Because medical expertise and safety matter.
I'm an NMC-registered nurse with over a decade of clinical experience. Before aesthetics, I spent 6 years as a cardiac nurse at KIMS Hospital. That background taught me that anatomical precision and protocol adherence aren't optional. They're essential.
I'm also BACN registered, JCCP verified, ACE Group registered, and a Royal College of Nursing member. I follow evidence-based protocols for every treatment. I use only licensed products from authorized suppliers. I maintain comprehensive insurance and emergency preparedness.
You're not getting a beauty therapist with a weekend certification. You're getting a registered medical professional who understands anatomy, physiology, and complication management.
Beyond credentials, I bring honest assessment. If Profhilo isn't right for you, I'll tell you and recommend better alternatives. I don't chase sales. I chase optimal patient outcomes.

